PRDM2 Antibody

Product Specifications

Background

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7799

Swiss Prot

Q13029

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PRDM2 (NP_036363.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 300kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PRDM2

Positive Control 2

LO2

Positive Control 3

MCF7

Positive Control 4

Mouse brain

Positive Control 5

Mouse liver

Positive Control 6

Rat brain

NCBI Official Name

PR/SET domain 2

NCBI Organism

Homo sapiens

Other Product Names

HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain zinc finger protein 2, GATA-3 binding protein G3B, MTE-binding protein, PR domain 2, PR domain containing 2, with ZNF domain, PR domain-containing protein 2, lysine N-methyltransferase 8, retinoblastoma protein-binding zinc finger protein, retinoblastoma protein-interacting zinc finger protein, zinc finger protein RIZ, zinc-finger DNA-binding protein