AADAT Antibody
Product Specifications
Background
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
51166
Swiss Prot
Q8N5Z0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
AADAT
Positive Control 2
22Rv1
Positive Control 3
293T
Positive Control 4
Mouse kidney
Positive Control 5
Rat kidney
NCBI Official Name
Aminoadipate aminotransferase
NCBI Organism
Homo sapiens
Other Product Names
AADAT, KAT2, KATII
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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