SPTB Antibody

Product Specifications

Background

This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.

NCBI Gene ID

6710

Swiss Prot

P11277

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2080-2180 of human SPTB (NP_001020029.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

K-562

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 256kDa

Fragment

IgG

Symbol

SPTB

Positive Control 2

Mouse brain

NCBI Official Name

Spectrin beta, erythrocytic

NCBI Organism

Homo sapiens

Other Product Names

EL3, HS2, HSPTB1, SPH2, spectrin beta chain, erythrocytic, Sp beta, beta-I spectrin, membrane cytoskeletal protein, spectrin beta Tandil, spectrin beta chain, erythrocyte