TONSL Antibody
Product Specifications
Background
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
NCBI Gene ID
4796
Swiss Prot
Q96HA7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-390 of human TONSL (NP_038460.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 151kDa
Fragment
IgG
Symbol
TONSL
Positive Control 2
Rat spleen
Positive Control 3
Mouse brain
NCBI Official Name
Tonsoku-like, DNA repair protein
NCBI Organism
Homo sapiens
Other Product Names
NFKBIL2, FLJ40087, IKBR, NFKBIL2
Tested Applications
WB, IHC
Physical Properties
Liquid
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