MYO6 Antibody
Product Specifications
Background
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
4646
Swiss Prot
Q9UM54
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-756
Calculated Molecular Weight
Observed: 150kDa
Fragment
IgG
Symbol
MYO6
Positive Control 2
Mouse brain
Positive Control 3
Mouse kidney
NCBI Official Name
Myosin VI
NCBI Organism
Homo sapiens
Other Product Names
DFNA22, DFNB37, unconventional myosin-VI, unconventional myosin-6
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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