CRHBP Antibody
Product Specifications
Background
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
NCBI Gene ID
1393
Swiss Prot
P24387
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 221-322 of human CRHBP (NP_001873.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CRHBP
Positive Control 2
LO2
Positive Control 3
293T
NCBI Official Name
Corticotropin releasing hormone binding protein
NCBI Organism
Homo sapiens
Other Product Names
CRF-BP, CRFBP, corticotropin-releasing factor-binding protein, CRF-binding protein, CRH-BP
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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