PGA5 Antibody
Product Specifications
Background
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
NCBI Gene ID
5222
Swiss Prot
P0DJD9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA5 (NP_055039.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PGA5
Positive Control 2
HT-29
Positive Control 3
293T
Positive Control 4
Mouse brain
Positive Control 5
Mouse stomach
Positive Control 6
Rat brain
NCBI Official Name
Pepsin A-5
NCBI Organism
Homo sapiens
Other Product Names
Pepsin A-5, Pepsinogen-5, PGA5
Tested Applications
WB
Physical Properties
Liquid
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