ATP6V1D Antibody
Product Specifications
Background
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.
NCBI Gene ID
51382
Swiss Prot
Q9Y5K8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human ATP6V1D (NP_057078.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-711
Calculated Molecular Weight
Observed: 35kDa
Fragment
IgG
Symbol
ATP6V1D
Positive Control 2
293T
Positive Control 3
HeLa
Positive Control 4
Mouse lung
Positive Control 5
Mouse brain
NCBI Official Name
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
NCBI Organism
Homo sapiens
Other Product Names
ATP6V1D, ATP6M, V-ATPase subunit D, VPATPD, V-type proton ATPase subunit D, Vacuolar H-ATPase subunit D, Vacuolar proton pump D subunit, Vacuolar proton pump subunit D, VMA8, V-ATPase d subunit, Vacuolar ATPase subunit D, VATD
Tested Applications
WB, IHC
Physical Properties
Liquid
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