DRD2 Antibody
Product Specifications
Background
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
NCBI Gene ID
1813
Swiss Prot
P14416
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
DRD2
Positive Control 2
Mouse brain
Positive Control 3
Rat brain
NCBI Official Name
D (2) dopamine receptor
NCBI Organism
Homo sapiens
Other Product Names
D (2) dopamine receptor, Dopamine D2 receptor, DRD2
Tested Applications
WB
Physical Properties
Liquid
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