F5 Antibody
Product Specifications
Background
This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.
NCBI Gene ID
2153
Swiss Prot
P12259
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-510 of human F5 (NP_000121.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Human plasma
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 310kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
F5
Positive Control 2
Human platelet
NCBI Official Name
Coagulation factor V
NCBI Organism
Homo sapiens
Other Product Names
FVL, PCCF, RPRGL1, THPH2, coagulation factor V, activated protein c cofactor, coagulation factor V (proaccelerin, labile factor), coagulation factor V jinjiang A2 domain, factor V Leiden
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
