GNAL Antibody

Product Specifications

Background

This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

2774

Swiss Prot

P38405

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GNAL (NP_892023.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 44kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GNAL

Positive Control 2

Rat brain

NCBI Official Name

G protein subunit alpha L

NCBI Organism

Homo sapiens

Other Product Names

DYT25, guanine nucleotide-binding protein G (olf) subunit alpha, adenylate cyclase-stimulating G alpha protein, olfactory type, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type