POLE2 Antibody

Product Specifications

Background

DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B) . Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

NCBI Gene ID

5427

Swiss Prot

P56282

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 59kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

POLE2

Positive Control 2

Mouse heart

NCBI Official Name

DNA polymerase epsilon 2, accessory subunit

NCBI Organism

Homo sapiens

Other Product Names

DPE2, DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, polymerase (DNA directed), epsilon 2 (p59 subunit), polymerase (DNA directed), epsilon 2, accessory subunit, polymerase (DNA) epsilon 2, accessory subunit