RAB7A Antibody
Product Specifications
Background
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
NCBI Gene ID
7879
Swiss Prot
P51149
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RAB7A (NP_004628.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Symbol
RAB7A
Positive Control 2
HeLa
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
NCBI Official Name
RAB7A, member RAS oncogene family
NCBI Organism
Homo sapiens
Other Product Names
RAB7A, CMT2B, PRO2706, RAB7, Ras-associated protein RAB7, Ras-related protein Rab-7a, PSN
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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