TMEM27 Antibody
Product Specifications
Background
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.
NCBI Gene ID
57393
Swiss Prot
Q9HBJ8
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human TMEM27 (NP_065716.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 29kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TMEM27
Positive Control 2
Mouse pancreas
Positive Control 3
Rat kidney
NCBI Official Name
Collectrin, amino acid transport regulator
NCBI Organism
Homo sapiens
Other Product Names
NX-17, NX17, TMEM27, collectrin, kidney-specific membrane protein, transmembrane protein 27
Tested Applications
WB
Physical Properties
Liquid
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