ACKR3 Antibody

Product Specifications

Background

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV) . Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

NCBI Gene ID

57007

Swiss Prot

P25106

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACKR3 (NP_064707.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

Raji

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ACKR3

Positive Control 2

A-549

Positive Control 3

U-87MG

Positive Control 4

Mouse lung

Positive Control 5

Mouse brain

Positive Control 6

Rat brain

NCBI Official Name

Atypical chemokine receptor 3

NCBI Organism

Homo sapiens

Other Product Names

ACKR3, atypical chemokine receptor 3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1, C-X-C chemokine receptor type 7, G protein-coupled receptor, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, chemokine (C-X-C motif) recepto