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ERCC3 Antibody

Product Specifications

Background

This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

2071

Swiss Prot

P19447

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 512-782 of human ERCC3 (NP_000113.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Transcription

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=14-588

Calculated Molecular Weight

Observed: 89kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ERCC3

Positive Control 2

Mouse kidney

Positive Control 3

Rat kidney

NCBI Official Name

Excision repair cross-complementing rodent repair deficiency, complementation group 3

NCBI Organism

Homo sapiens

Other Product Names

ERCC3, BTF2, GTF2H, RAD25, TFIIH p89, TFIIH, XPB, BTF2 p89, XPBC, TFIIH 89 kDa subunit

Tested Applications

WB

Physical Properties

Liquid

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