CUL4B Antibody
Product Specifications
Background
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8450
Swiss Prot
Q13620
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human CUL4B (NP_003579.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-584
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
CUL4B
Positive Control 2
SH-SY5Y
Positive Control 3
HeLa
Positive Control 4
Mouse brain
Positive Control 5
Mouse testis
Positive Control 6
Mouse liver
NCBI Official Name
Cullin-4B
NCBI Organism
Homo sapiens
Other Product Names
Cullin-4B, CUL-4B, CUL4B, KIAA0695
Tested Applications
WB, IP
Physical Properties
Liquid
Curated Selection
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