AREG Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha) . The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
NCBI Gene ID
374
Swiss Prot
P15514
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 44kDa
Fragment
IgG
Symbol
AREG
Positive Control 2
Rat testis
NCBI Official Name
Amphiregulin
NCBI Organism
Homo sapiens
Other Product Names
Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF, AREG, SDGF
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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