PTX3 Antibody

Product Specifications

Background

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.

NCBI Gene ID

5806

Swiss Prot

P26022

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-240 of human PTX3 (NP_002843.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors, Immunology

Purification

Affinity purification

Positive Control

A375

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PTX3

Positive Control 2

HL-60

Positive Control 3

HepG2

Positive Control 4

Jurkat

Positive Control 5

NIH/3T3

Positive Control 6

Mouse liver

NCBI Official Name

Pentraxin-related protein PTX3

NCBI Organism

Homo sapiens

Other Product Names

Pentraxin-related protein PTX3, Pentaxin-related protein PTX3, Tumor necrosis factor alpha-induced protein 5, TNF alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3, TNFAIP5, TSG14