HMGN3 Antibody

Product Specifications

Background

The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1.

NCBI Gene ID

9324

Swiss Prot

Q15651

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-77 of human HMGN3 (NP_620058.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 12kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

HMGN3

NCBI Official Name

High mobility group nucleosomal binding domain 3

NCBI Organism

Homo sapiens

Other Product Names

PNAS-24, PNAS-25, TRIP7, high mobility group nucleosome-binding domain-containing protein 3, TR-interacting protein 7, thyroid hormone receptor interacting protein 7