NCR3 Antibody
Product Specifications
Background
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
259197
Swiss Prot
O14931
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human NCR3 (NP_667341.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Stem Cell
Purification
Affinity purification
Positive Control
Rat liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NCR3
NCBI Official Name
Natural cytotoxicity triggering receptor 3
NCBI Organism
Homo sapiens
Other Product Names
1C7, CD337, LY117, MALS, NKp3natural cytotoxicity triggering receptor 3, NK-p3activating NK-A1 receptor, activating natural killer receptor p3lymphocyte antigen 117, natural killer cell p30-related protein
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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