NCR3 Antibody

Product Specifications

Background

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

259197

Swiss Prot

O14931

Host

Rabbit

Reactivity

Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human NCR3 (NP_667341.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Stem Cell

Purification

Affinity purification

Positive Control

Rat liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NCR3

NCBI Official Name

Natural cytotoxicity triggering receptor 3

NCBI Organism

Homo sapiens

Other Product Names

1C7, CD337, LY117, MALS, NKp3natural cytotoxicity triggering receptor 3, NK-p3activating NK-A1 receptor, activating natural killer receptor p3lymphocyte antigen 117, natural killer cell p30-related protein