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TOPBP1 Antibody

Product Specifications

Background

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

NCBI Gene ID

11073

Swiss Prot

Q92547

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Affinity purification

Positive Control

Mouse ovary

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 130kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TOPBP1

Positive Control 2

Rat testis

NCBI Official Name

DNA topoisomerase II binding protein 1

NCBI Organism

Homo sapiens

Other Product Names

Dpb11, TOP2BP1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, topoisomerase (DNA) II binding protein 1

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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