TOPBP1 Antibody
Product Specifications
Background
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
NCBI Gene ID
11073
Swiss Prot
Q92547
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
Mouse ovary
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 130kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TOPBP1
Positive Control 2
Rat testis
NCBI Official Name
DNA topoisomerase II binding protein 1
NCBI Organism
Homo sapiens
Other Product Names
Dpb11, TOP2BP1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, topoisomerase (DNA) II binding protein 1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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