TCEB1 Antibody
Product Specifications
Background
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
NCBI Gene ID
6921
Swiss Prot
Q15369
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-112 of human TCEB1 (NP_001191791.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-476
Calculated Molecular Weight
Observed: 12kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TCEB1
Positive Control 2
PC-3
Positive Control 3
MCF7
Positive Control 4
HepG2
Positive Control 5
Mouse liver
Positive Control 6
Mouse lung
NCBI Official Name
Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
NCBI Organism
Homo sapiens
Other Product Names
TCEB1, SIII, eloC
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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