STXBP2 Antibody
Product Specifications
Background
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
NCBI Gene ID
6813
Swiss Prot
Q15833
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 66kDa
Fragment
IgG
Symbol
STXBP2
Positive Control 2
Jurkat
Positive Control 3
Mouse testis
Positive Control 4
Mouse thymus
NCBI Official Name
Syntaxin-binding protein 2
NCBI Organism
Homo sapiens
Other Product Names
Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B, STXBP2, UNC18B
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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