SET Antibody
Product Specifications
Background
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT) . This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6418
Swiss Prot
Q01105
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET (NP_003002.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-466
Calculated Molecular Weight
Observed: 34kDa
Fragment
IgG
Symbol
SET
Positive Control 2
293T
Positive Control 3
BT-474
Positive Control 4
HL-60
Positive Control 5
NIH/3T3
Positive Control 6
Mouse spleen
NCBI Official Name
SET nuclear oncogene
NCBI Organism
Homo sapiens
Other Product Names
SET, SET translocation (myeloid leukemia-associated), 2PP2A, I2PP2A, PHAPII, TAF-IBETA, SET, translocation, IGAAD, inhibitor-2 of protein phosphatase-2A, Inhibitor of GZMA-activated DNAse, TAF-I, IPP2A2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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