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PTHLH Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2) . Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.

NCBI Gene ID

5744

Swiss Prot

P12272

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 74-130 of human PTHLH (NP_945316.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

PTHLH

NCBI Official Name

Parathyroid hormone-like hormone

NCBI Organism

Homo sapiens

Other Product Names

HHM, PLP, BDE2, PTHR, PTHRP, Parathyroid hormone-related protein, Parathyroid hormone-like protein, PTH-rP

Tested Applications

WB, IHC

Physical Properties

Liquid

Frequently Asked Questions

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