PSMA3 Antibody
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
NCBI Gene ID
5684
Swiss Prot
P25788
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human PSMA3 (NP_002779.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-431
Calculated Molecular Weight
Observed: 28kDa
Fragment
IgG
Symbol
PSMA3
Positive Control 2
DU145
Positive Control 3
HL-60
Positive Control 4
PC-3
Positive Control 5
Mouse liver
Positive Control 6
Mouse spleen
NCBI Official Name
Proteasome subunit alpha 3
NCBI Organism
Homo sapiens
Other Product Names
HC8, PSC3, proteasome subunit alpha type-3, macropain subunit C8, multicatalytic endopeptidase complex subunit C8, proteasome (prosome, macropain) subunit, alpha type, 3, proteasome component C8, proteasome subunit C8, testicular secretory protein Li 43
Tested Applications
WB, IF, IP
Physical Properties
Liquid
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