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NRF2 Antibody

Product Specifications

Background

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

NCBI Gene ID

4780

Swiss Prot

Q16236

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 366-605 of human NRF2 (NP_006155.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Transcription

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 75kDa/105kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NFE2L2

Positive Control 2

A-549

Positive Control 3

HeLa

NCBI Official Name

Nuclear factor, erythroid 2-like 2

NCBI Organism

Homo sapiens

Other Product Names

NFE2L2, NRF2

Tested Applications

WB, IF

Physical Properties

Liquid

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