F11R Antibody

Product Specifications

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

NCBI Gene ID

50848

Swiss Prot

Q9Y624

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

OVCAR3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 40kDa

Fragment

IgG

Symbol

F11R

Positive Control 2

SW620

Positive Control 3

Mouse liver

NCBI Official Name

F11 receptor

NCBI Organism

Homo sapiens

Other Product Names

Platelet adhesion molecule, platelet F11 receptor, junctional adhesion molecule A, junctional adhesion molecule 1, OTTHUMP00000027881, OTTHUMP00000027880, PAM-1, KAT, JCAM, JAMA, JAM1, JAM-A, JAM-1, JAM, CD321, F11 receptor, F11R, UNQ264/PRO301