Beta 2 Microglobulin Antibody, KO Validated
Product Specifications
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
NCBI Gene ID
567
Swiss Prot
P61769
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 12kDa
Fragment
IgG
Symbol
B2M
Positive Control 2
COS7
Positive Control 3
HeLa
Positive Control 4
K-562
Positive Control 5
Mouse liver
Positive Control 6
Mouse spleen
NCBI Official Name
Beta-2-microglobulin
NCBI Organism
Homo sapiens
Other Product Names
B2M Antibody: Beta-2-microglobulin
Tested Applications
WB, IHC, IP
Physical Properties
Liquid
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