EXOC4 Antibody
Product Specifications
Background
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
60412
Swiss Prot
Q96A65
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human EXOC4 (NP_068579.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 122kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
EXOC4
Positive Control 2
Jurkat
Positive Control 3
Mouse brain
Positive Control 4
Mouse thymus
Positive Control 5
Mouse liver
Positive Control 6
Rat brain
NCBI Official Name
Exocyst complex component 4
NCBI Organism
Homo sapiens
Other Product Names
SEC8, SEC8L1, Sec8p, exocyst complex component 4, SEC8-like 1, exocyst complex component Sec8
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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