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SARS2 Antibody

Product Specifications

Background

This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA (Ser) and participates in the biosynthesis of selenocysteinyl-tRNA (sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

NCBI Gene ID

54938

Swiss Prot

Q9NP81

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 289-518 of human SARS2 (NP_060297.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Symbol

SARS2

Positive Control 2

Mouse liver

Positive Control 3

Mouse kidney

NCBI Official Name

Serine--tRNA ligase, mitochondrial

NCBI Organism

Homo sapiens

Other Product Names

Serine--tRNA ligase, mitochondrial, SerRSmt, Seryl-tRNA synthetase, SerRS, Seryl-tRNA (Ser/Sec) synthetase, SARS2, SARSM

Tested Applications

WB, IHC

Physical Properties

Liquid

Frequently Asked Questions

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