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PDE8A Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5151

Swiss Prot

O60658

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

Mouse testis

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=14-301

Calculated Molecular Weight

Observed: 93kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PDE8A

Positive Control 2

Mouse eye

Positive Control 3

Mouse liver

Positive Control 4

Rat testis

NCBI Official Name

Phosphodiesterase 8A

NCBI Organism

Homo sapiens

Other Product Names

PDE8A, Phosphodiesterase 8A, HsT19550

Tested Applications

WB

Physical Properties

Liquid

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