ACD Antibody

Product Specifications

Background

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

NCBI Gene ID

65057

Swiss Prot

Q96AP0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 58kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ACD

Positive Control 2

Mouse liver

Positive Control 3

Mouse spleen

Positive Control 4

Mouse testis

Positive Control 5

Rat liver

NCBI Official Name

ACD shelterin complex subunit and telomerase recruitment factor

NCBI Organism

Homo sapiens

Other Product Names

PIP1, PTOP, TINT1, TPP1, adrenocortical dysplasia protein homolog, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, adrenocortical dysplasia homolog