CYP26B1 Antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
56603
Swiss Prot
Q9NR63
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 213-512 of human CYP26B1 (NP_063938.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-277
Calculated Molecular Weight
Observed: 58-65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CYP26B1
Positive Control 2
Mouse lung
NCBI Official Name
Cytochrome P450, family 26, subfamily B, polypeptide 1
NCBI Organism
Homo sapiens
Other Product Names
CYP26B1, cytochrome P450, family 26, subfamily B, polypeptide 1, CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2, cytochrome P450 retinoid metabolizing protein, subfamily b, retinoic acid-metabolizing cytochrome , P450RAI2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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