CYP26B1 Antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

56603

Swiss Prot

Q9NR63

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 213-512 of human CYP26B1 (NP_063938.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Chemokines & Cytokines, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 58-65kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CYP26B1

Positive Control 2

Mouse lung

NCBI Official Name

Cytochrome P450, family 26, subfamily B, polypeptide 1

NCBI Organism

Homo sapiens

Other Product Names

CYP26B1, cytochrome P450, family 26, subfamily B, polypeptide 1, CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2, cytochrome P450 retinoid metabolizing protein, subfamily b, retinoic acid-metabolizing cytochrome , P450RAI2