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ARHGDIA Antibody, KO Validated

Product Specifications

Background

This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

396

Swiss Prot

P52565

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human ARHGDIA (NP_001172006.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=14-275

Calculated Molecular Weight

Observed: 25kDa

Fragment

IgG

Symbol

ARHGDIA

Positive Control 2

COS7

Positive Control 3

PC-12

Positive Control 4

Mouse lung

Positive Control 5

Mouse spleen

Positive Control 6

Mouse kidney

NCBI Official Name

Rho GDP dissociation inhibitor (GDI) alpha

NCBI Organism

Homo sapiens

Other Product Names

ARHGDIA, RHOGDI-1, RHOGDI, Rho GDP dissociation inhibitor (GDI) alpha, MGC117248, GDIA1

Tested Applications

WB, IF

Physical Properties

Liquid

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