PORCN Antibody

Product Specifications

Background

This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

NCBI Gene ID

64840

Swiss Prot

Q9H237

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 220-320 of human PORCN (NP_982299.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PORCN

Positive Control 2

HepG2

NCBI Official Name

Porcupine O-acyltransferase

NCBI Organism

Homo sapiens

Other Product Names

DHOF, FODH, MG61, PORC, PPN, protein-serine O-palmitoleoyltransferase porcupine, porcupine homolog, probable protein-cysteine N-palmitoyltransferase porcupine