ATP6AP1 Antibody

Product Specifications

Background

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.

NCBI Gene ID

537

Swiss Prot

Q15904

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 90-390 of human ATP6AP1 (NP_001174.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology

Purification

Affinity purification

Positive Control

THP-1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ATP6AP1

Positive Control 2

OVCAR3

Positive Control 3

PC-3

Positive Control 4

Mouse brain

NCBI Official Name

ATPase H+ transporting accessory protein 1

NCBI Organism

Homo sapiens

Other Product Names

16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3, V-type proton ATPase subunit S1, ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1, ATPase, H+ transporting, lysosomal accessory protein 1, ATPase, H+ transporting, lysosomal interacting protein 1, H-ATPase subunit, V-ATPase Ac45 subunit, V-ATPase S1 accessory protein, V-ATPase subunit S1, epididymis secretory sperm binding protein, protein XAP-3, vacuolar proton pump subunit S1