NAGS Antibody
Product Specifications
Background
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
NCBI Gene ID
162417
Swiss Prot
Q8N159
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 295-534 of human NAGS (NP_694551.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 58kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
NAGS
Positive Control 2
K-562
Positive Control 3
Mouse liver
Positive Control 4
Mouse small intestine
Positive Control 5
Mouse testis
Positive Control 6
Rat liver
NCBI Official Name
N-acetylglutamate synthase
NCBI Organism
Homo sapiens
Other Product Names
NAGS, AGAS, ARGA, MGC133025
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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