GSR Antibody
Product Specifications
Background
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
NCBI Gene ID
2936
Swiss Prot
P00390
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
GSR
Positive Control 2
HeLa
Positive Control 3
A-549
Positive Control 4
Jurkat
Positive Control 5
Mouse brain
Positive Control 6
Mouse heart
NCBI Official Name
Glutathione reductase
NCBI Organism
Homo sapiens
Other Product Names
GSR, MGC78522, HEL-75
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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