ANO6 Antibody
Product Specifications
Background
This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
196527
Swiss Prot
Q4KMQ2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 750-830 of human ANO6 (NP_001020527.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ANO6
Positive Control 2
Mouse liver
Positive Control 3
Rat brain
NCBI Official Name
Anoctamin-6
NCBI Organism
Homo sapiens
Other Product Names
Anoctamin-6, Small-conductance calcium-activated nonselective cation channel, SCAN channel, Transmembrane protein 16F, ANO6, TMEM16F
Tested Applications
WB
Physical Properties
Liquid
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