SEMA7A Antibody

Product Specifications

Background

This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD) . Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

NCBI Gene ID

8482

Swiss Prot

O75326

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 45-280 of human SEMA7A (NP_003603.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 75kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000

Symbol

SEMA7A

Positive Control 2

HT-29

Positive Control 3

Raji

NCBI Official Name

Semaphorin 7A (John Milton Hagen blood group)

NCBI Organism

Homo sapiens

Other Product Names

CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL, semaphorin-7A, JMH blood group antigen, John Milton Hagen blood group H-Sema K1, john-Milton-Hargen human blood group Ag, sema K1, sema L, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group), sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A, semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group), semaphorin-K1, semaphorin-L