RNF4 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

NCBI Gene ID

6047

Swiss Prot

P78317

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RNF4 (NP_001171938.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 21kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000

Symbol

RNF4

Positive Control 2

Mouse brain

Positive Control 3

Rat testis

NCBI Official Name

Ring finger protein 4

NCBI Organism

Homo sapiens

Other Product Names

RES4-26, SLX5, SNURF, E3 ubiquitin-protein ligase RNF4, E3 ubiquitin ligase RNF4, RING-type E3 ubiquitin transferase RNF4, small nuclear RING finger protein