KRAS Antibody
Product Specifications
Background
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
NCBI Gene ID
3845
Swiss Prot
P01116
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human KRAS
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22kDa
Fragment
IgG
Symbol
KRAS
Positive Control 2
HeLa
Positive Control 3
Raji
Positive Control 4
Mouse spleen
Positive Control 5
Mouse lung
Positive Control 6
Rat brain
NCBI Official Name
Kirsten rat sarcoma viral oncogene homolog
NCBI Organism
Homo sapiens
Other Product Names
KRAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2, NS, CFC2
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
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