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KRAS Antibody

Product Specifications

Background

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

NCBI Gene ID

3845

Swiss Prot

P01116

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human KRAS

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=14-182

Calculated Molecular Weight

Observed: 22kDa

Fragment

IgG

Symbol

KRAS

Positive Control 2

HeLa

Positive Control 3

Raji

Positive Control 4

Mouse spleen

Positive Control 5

Mouse lung

Positive Control 6

Rat brain

NCBI Official Name

Kirsten rat sarcoma viral oncogene homolog

NCBI Organism

Homo sapiens

Other Product Names

KRAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2, NS, CFC2

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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