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GGA2 Antibody

Product Specifications

Background

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

NCBI Gene ID

23062

Swiss Prot

Q9UJY4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_055859.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 72-80kDa

Fragment

IgG

Symbol

GGA2

Positive Control 2

Raji

Positive Control 3

MCF7

Positive Control 4

THP-1

Positive Control 5

22Rv1

Positive Control 6

Mouse brain

NCBI Official Name

Golgi-associated, gamma adaptin ear containing, ARF binding protein 2

NCBI Organism

Homo sapiens

Other Product Names

GGA2, KIAA1080, VEAR

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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