TARDBP Antibody
Product Specifications
Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
NCBI Gene ID
23435
Swiss Prot
Q13148
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Symbol
TARDBP
Positive Control 2
Jurkat
Positive Control 3
SW620
Positive Control 4
HT-29
Positive Control 5
A-673
Positive Control 6
Es-2
NCBI Official Name
TAR DNA binding protein
NCBI Organism
Homo sapiens
Other Product Names
TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43
Tested Applications
WB, IHC, IF, IP, RIP
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7226549-03 5x 96 Well
Bovine Costars family protein C6orf115 (C6orf115) ELISA Kit
Ask
View Details 
MBS7226549-04 10x 96 Well
Bovine Costars family protein C6orf115 (C6orf115) ELISA Kit
Ask
View Details 