KLRB1 Antibody
Product Specifications
Background
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.
NCBI Gene ID
3820
Swiss Prot
Q12918
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 73-140 of human KLRB1 (NP_002249.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
KLRB1
Positive Control 2
Mouse liver
NCBI Official Name
Killer cell lectin-like receptor subfamily B, member 1
NCBI Organism
Homo sapiens
Other Product Names
CLEC5B, NKRP1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, NKR-P1A, NKR, CD161, NKR-P1, hNKR-P1A
Tested Applications
WB
Physical Properties
Liquid
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