SPR Antibody
Product Specifications
Background
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4) . Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
NCBI Gene ID
6697
Swiss Prot
P35270
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human SPR (NP_003115.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
BxPC-3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 31kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SPR
Positive Control 2
Jurkat
NCBI Official Name
Sepiapterin reductase
NCBI Organism
Homo sapiens
Other Product Names
Sepiapterin reductase, SPR, SPR
Tested Applications
WB
Physical Properties
Liquid
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